In Powerpuff Girls Z, The Rowdyruff Boys resemble a street gang. They dress in black windbreakers lined with their trademark colors and skate shoes that increase their speed. Unlike the American series, where the boys were equal height and same age as the girls, the trio appeared somewhat shorter and younger than the girls in the anime.
When they are introduced in the show, they start to dance off as if in a rap video. They were created by Mojo Jojo after breaking into the Professor's lab and stealing a canister of Chemical Z. Mojo also used Momoko's curly straw, Miyako's used cotton swab, Kaoru's smelly sweat sock, and snips of Mojo's hair to create them.
The Rowdyruff Boys Z love to disgust and annoy the citizens of New Townsville, as well as the Powerpuff Girls Z, who they refer to as "old hags." They have no respect for anyone, including Mojo Jojo who they refer to as "Mama." The boys, like the girls, have weapons. Brick uses Momoko's curly straw to fire spitballs, Boomer uses Miyako's cotton swab to throw earwax, and Butch uses Kaoru's smelly sock as a boomerang. They love pulling pranks on innocent people. They even gross out the girls as well as embarrassing them by spitballing, earwax, foul odor and flipping up their skirts. They later appear in the episode Powerpuff Rowdyruff Boys, in which the boys steal the Powerpuff Girls Z outfits and weapons, and, despite being inexperienced in using the weapons, manage to convince everyone that they're the Powerpuff Girls Z. However, they relinquish the outfits when the girliness of the suits is pointed out. Later, in Girls, Beyond Time and Space, the boys show up at the villains meeting, demanding to know why they weren't invited. The Gangreen Gang point out they are not real monsters. It is then that they first discover that they were created from Mojo and The Girls' DNA, causing them to react in a funny combination of shock and depression. When they turn to leave from the scene, Him gives them the opportunity to be turned into "real monsters," giving them more stronger and evil powers for a short time. They are defeated by kisses blown to them by the Powerpuff Girls Z, but rather than exploding, they go into a state of unconscious shock. In the following episode, Girls, The Last Battle, when HIM is destroyed, the boys are seen waking up from their shock and instantly start fighting with everyone else. They are last seen being tossed up and down in the air by the Powerpuff Girls Z.
- Their Chinese names are the same two Chinese words, not actually translated by original English names. Their names in Chinese are "比比" for Brick, "布布" for Boomer and "巴巴" for Butch. No meaning, just translated from the first two letters pronunciation.