|Twiggy in her cage|
|Nickname:||Little Rat by Princess|
|First appearance:||"Stuck Up, Up, and Away"|
|Last appearance:||"Gettin' Twiggy With It"|
|Voice actor:||Frank Welker|
Twiggy is the Pokey Oaks' kindergarten's class hamster. Every Friday, a Pokey Oak's student has to take Twiggy home and care for her. She was once turned into a monster hamster in "Gettin' Twiggy With It" because Mitch Mitchelson flushed her down the toilet and she got mutated by a radioactive chemical in the sewer, similar to Peepi's case in the Invader Zim episode "Hamstergeddon", where he is turned into a monster by Zim. At the end of the episode, she tries to destroy and eat Mitch as revenge for cruelly torturing her. She also dislikes Princess Morbucks, who insulted her. She kept running really fast on her hamster wheel, causing her cage to fall off the table and break.
- Stuck Up, Up, and Away
- Daylight Savings (seen sleeping in a cameo appearance)
- Gettin' Twiggy With It
- It is unknown if she ever gets turned back to a normal hamster, after Gettin' Twiggy With It.
- She is similar to Peepi from the Invader Zim episode "Hamstergeddon", as both are class pets and are turned into monsters (Peepi by Zim and her by Mitch).
- Blossom accidently called her a "him" once.